Jin Hee, a dietitian, had a satisfying life until she met medical student Chang Min. Despite his wealthy family's opposition, they married. Chang Min later became a pharmaceutical salesman, straining their relationship further. The disapproval of Chang Min's family made matters worse, leading to their divorce. Afterward, Jin Hee pursued a medical career and became an intern. Chang Min also completed medical school and started working as an intern. Fate reunites them in the hospital's emergency room, where they must work together.
Jung Yeol and Na Ra fell in love with each other and got married. During their marriage, they have grown to hate each other due to their personality differences. They decide to get a divorce. A month later, their divorce will be finalized. But, on the day that they applied for a divorce, they get into a car accident. When they wake up at the hospital, they have both lost their memories and do not remember each other.