Hm, maybe Priceless. The main character gets fired from his job and has to start over by himself - he doesn't even have a home. I don't remember if there was any romance. Probably not, or if there was it wasn't important for the plot.
Also First Half of My Life. The main character is a rich, spoiled housewife but she gets divorced and has to start working. She struggles a lot. But this drama might not be exactly what you're looking for. It is also about her family problems (mother, sister) and her husband and his new wife, and there is a little bit of romance.