Basically what the title says. It's possible to find good dramas, that don't focus on romance (crime, mystery, comedies or any other genre), but they rarely have any significant female characters.
Any genre, any country although i prefer Korean and Japanese ones.

Women centered dramas with little to no romance:

  • Doctor X
  • Nobody Knows
  • Nurse In Action
  • Mother
  • Miss Sherlock
  • Nagis long vacation
  • Kenja No Ai
  • Nothing But Gold Can Stay
  • Dear Patient
  • Woman of Dignity
  • Parting Left
  • Girl K
  • Avengers Social Club
  • Orphan black

Ensemble cast centric dramas but with significant and strong female lead:

  • Signal
  • Stranger
  • My mister
  • Diary of a prosecutor
  • Unnatural
  • Money Game
  • Dear my friends
  • The guest
  • Partners for justice

^ pretty great, extensive list above

Here are more dramas with great female leads and no romance

  • Black Dog
  • Angry Mom
  • Sky Castle
  • Stranger
  • Children of Nobody

1. Shokuzai (2012)
2. Ishi no Mayu (2015)
3. Garasu no Ashi (2015)
4. Kaitou Yamaneko (2016)*
5. Rakuen (2017)
6. Saka no Tochu no le  (2019)

(the fourth recommended series is focused on three leads in which one is female)

 Czakhareina:

Women centered dramas with little to no romance:

  • Doctor X
  • Nobody Knows
  • Nurse In Action
  • Mother
  • Miss Sherlock
  • Nagis long vacation
  • Kenja No Ai
  • Nothing But Gold Can Stay
  • Dear Patient
  • Woman of Dignity
  • Parting Left
  • Girl K
  • Avengers Social Club
  • Orphan black

Ensemble cast centric dramas but with significant and strong female lead:

  • Signal
  • Stranger
  • My mister
  • Diary of a prosecutor
  • Unnatural
  • Money Game
  • Dear my friends
  • The guest
  • Partners for justice

Wow thank you so much! There are so many to choose from!

 sobak:

^ pretty great, extensive list above

Here are more dramas with great female leads and no romance

  • Black Dog
  • Angry Mom
  • Sky Castle
  • Stranger
  • Children of Nobody

Thank you! Children of Nobody seems very interesting.

 Irene:

1. Shokuzai (2012)
2. Ishi no Mayu (2015)
3. Garasu no Ashi (2015)
4. Kaitou Yamaneko (2016)*
5. Rakuen (2017)
6. Saka no Tochu no le  (2019)

(the fourth recommended series is focused on three leads in which one is female)

Thanks a lot! First two seems great as i'm a fan of mysteries :)

  • Signal
  • Stranger
  • Cold Case
  • Ms Temper and Nam Jung Gi
  • Strawberry night
  • The good wife
  • Confidence man
  • Lookout
  • The Guest
  • Unnatural
  • 1 litre no namida
  • Mystic Pop-up bar
 fanitha:
  • Signal
  • Stranger
  • Cold Case
  • Ms Temper and Nam Jung Gi
  • Strawberry night
  • The good wife
  • Confidence man
  • Lookout
  • The Guest
  • Unnatural
  • 1 litre no namida
  • Mystic Pop-up bar

Thank you! Never heard of The Confidence Man, which looks pretty interesting!

Dr. Frost, it´s a psychological, crime, detective and medical drama, 10 episodes, but there´s a male + female lead not just a female lead

 sayourixx:

Dr. Frost, it´s a psychological, crime, detective and medical drama, 10 episodes, but there´s a male + female lead not just a female lead

Thanks, i'll check this one :)