Unlike how the title of this drama is based on the two characters' names being ichi and ni, 1 and 2, this is not some light-hearted romance comedy.

I find this series to hold one of the most mature look and handling on topics of how intimacy and sexual desires effects the romantic relationship.

It has possibly given me more understanding to people who cannot conform to societal standards and expectations for their lack of outwardly affection.
A standard that is ironically, typically perpetuated by popular media such as tv dramas and mangas.

Spoilers ahead:

Our main perspective character, ichi, suffers from committal issues and has trouble with performing acts of physical intimacy with her husband due to childhood trama from her parents.

We as the viewer gets glimpses of her life navigating how to love her husband with how she is, and her husband as well. Their odd situation led to them hurting the people around them as well as themselves in the process.

Life is messy, as much as we try to keep it organized, just as Ichi's room becomes a mess to reflect her inner turmoil.

The ending was expected, as perfectly imperfect as it seems, and it is in a sense, an open ending, as they still love each other deeply, but it is because of how much they love that they cannot live together.

It is troubling to see your loved one struggle and suffer because of you. It is troubling when you feel like you are walking on eggshells when you are in the same room.

They indeed understand each other, in the end. Therefore the question of is there anything I can help you with is met with silence.

Because the mode of depression is caused by his presence, by her inability to give him the life he dreams of, and that is often true, and sometimes love is expressed by letting go.