Both dramas are very funny, cheerful, uplifting comedies with the focus on romance between a company CEO and their staff member.
Both series take place both in real life and in a video game. Love O2O is more romantic, while Memories of the Alhambra is more action-thriller-mystery. Both are well written with brilliant actors and engaging characters.
Both titles are heartfelt romances between childhood friends. The main characters are in their 30s in both dramas. The interactions between the leads are both funny and endearing, and hit you right in the feels.