Sotus does have a female who identifies as lesbian. Very side character, but it is woven in nicely. Not quite sure how old they would be in it, but university age. So I am assuming 18+. It's certainly not something you would watch just for that, as it isn't the focus by any means and she has no romantic interest. Might not be quite what you are looking for, but figured I'd mention it :)
Also We Are Gamily. I haven't seen it, but unless the trailer seriously misrepresented all the things, it would fit.